Top Pickens County Hotels: 2026 Best Hotels in Pickens County - Expedia

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Pickens County
South Carolina
United States of America
Hotels
Expedia.com

Vacation Rentals in Pickens County Pickens County Flights Car Rentals in Pickens County Pickens County Vacations

A lake surrounded by forested hills.

A lake surrounded by forested hills.

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Top Cities in Pickens County

An aerial view of a university campus with multiple buildings, green spaces, and a prominent clock tower.

A lake surrounded by forested hills.

A dry grassland with a few trees, a red building, and mountains in the background.

A waterfall cascading over a rocky ledge into a calm river surrounded by lush greenery.

A mountain range with a sunset.

A lake surrounded by forested hills.

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Our top choices for Pickens County hotels

A spacious indoor dining area with multiple tables and chairs, a food service counter, and a modern architectural design with balconies.

A spacious indoor area with multiple seating arrangements, a ping pong table, and a bar area with purple accents.

A hotel room with a bed, a desk, a TV, a mirror, and a nightstand with a lamp.

A lobby with seating areas, a reception desk, and a patterned wall.

1. Best Western Plus Clemson Hotel & Conference Center

Best Western Plus Clemson Hotel & Conference Center

2.5 star property

Clemson

8.0 out of 10, Very good, (1,005 reviews)

8.0/10

Very good

(1,005 reviews)

"Great place to stay."

"Great place to stay."

United States

David

$101 nightly

The price is $112

$112 total

Sep 24 - Sep 25

Total with taxes and fees

Best Western Plus Clemson Hotel & Conference Center

A multi-level interior with a spiral staircase, wooden railings, and a seating area with tables and chairs.

An outdoor patio with wicker furniture, a round table, and a fountain.

A spacious restaurant with high ceilings, wooden flooring, and a mix of modern and classic furniture.

A modern bar area with a wooden ceiling, green bar stools, and a bar counter.

2. The Shepherd Hotel Downtown Clemson

The Shepherd Hotel Downtown Clemson

4.0 star property

Clemson

9.8 out of 10, Exceptional, (891 reviews)

9.8/10

Exceptional

(891 reviews)

"Always a wonderful stay!"

"Always a wonderful stay!"

United States

Laurrie

$239 nightly

The price is $265

$265 total

Sep 27 - Sep 28

Total with taxes and fees

The Shepherd Hotel Downtown Clemson

A reception area with a reception desk, a sofa, a staircase, and a wall with artwork.

A wall with a decorative design featuring a building, trees, and a sky with clouds.

A dining area with a brick floor, wooden tables, and chairs, a kitchen counter with appliances, and large windows offering a view of the outside.

A tiger mascot holding a sign with "HOWARD'S ROCK" text, a staircase, and a desk with a computer.

3. Inn @ Clemson

2.5 star property

Clemson

8.0 out of 10, Very good, (1,005 reviews)

8.0/10

Very good

(1,005 reviews)

"Great breakfast and location"

"Great breakfast and location"

United States

Terry

$82 nightly

The price is $91

$91 total

Sep 23 - Sep 24

Total with taxes and fees

A golf course with a water body, trees, and a distant view of a bridge.

A modern building with a central entrance, surrounded by a well-maintained lawn and trees.

A large, curved swimming pool with lounge chairs and umbrellas, surrounded by landscaped areas and a building in the background.

A golf course with a clubhouse, surrounded by dense trees and a large body of water.

4. Clemson University's James F. Martin Inn

Clemson University's James F. Martin Inn

3.0 star property

Clemson

9.4 out of 10, Exceptional, (1,002 reviews)

9.4/10

Exceptional

(1,002 reviews)

"Great property! We really enjoyed our stay!!"

"Great property! We really enjoyed our stay!!"

United States

Jennifer

$127 nightly

The price is $141

$141 total

Sep 23 - Sep 24

Total with taxes and fees

Clemson University's James F. Martin Inn

A modern bar area with a menu board, bar stools, and a countertop with various items.

A modern dining area with a bar, bar stools, and a patterned rug.

A Courtyard Marriott hotel with a brick facade, multiple floors, and a covered entrance area.

An outdoor patio with a circular fire pit surrounded by wicker furniture and a pergola overhead.

5. Courtyard Marriott Clemson

Courtyard Marriott Clemson

3.0 star property

Clemson

9.0 out of 10, Wonderful, (578 reviews)

9.0/10

Wonderful

(578 reviews)

"The staff were so friendly and accommodating. The property was very clean and room was spacious."

"The staff were so friendly and accommodating. The property was very clean and room was spacious."

United States

kim

$143 nightly

The price is $159

$159 total

Sep 28 - Sep 29

Total with taxes and fees

Courtyard Marriott Clemson

A hotel hallway with a carpeted floor, light-colored walls, and doors on both sides.

A hotel room with a bed, a sofa, a small round table, a lamp, and artwork on the wall.

A swimming pool with lounge chairs and a no diving sign.

A Comfort Inn & Suites hotel with a modern design, featuring a prominent sign and a well-maintained outdoor area with landscaping.

6. Comfort Inn & Suites Clemson - University Area

Comfort Inn & Suites Clemson - University Area

2.5 star property

Clemson

8.4 out of 10, Very good, (1,008 reviews)

8.4/10

Very good

(1,008 reviews)

"Great location when visiting our Clemson student."

"Great location when visiting our Clemson student."

United States

Jinna M

$105 nightly

The price is $116

$116 total

Oct 18 - Oct 19

Total with taxes and fees

Comfort Inn & Suites Clemson - University Area

A spacious hallway with a wooden ceiling, a sofa, a chair, and a lamp.

A modern restaurant with a marble-top dining table, blue upholstered chairs, and a variety of food items displayed in the background.

A hotel lobby with a long corridor, seating areas, and a reception desk.

A brick building with a sign reading "The Inn at Patrick Square".

7. The Inn at Patrick Square

The Inn at Patrick Square

3.5 star property

Clemson

9.8 out of 10, Exceptional, (917 reviews)

9.8/10

Exceptional

(917 reviews)

"This is a great hotel. Location is excellent. Interior of the hotel is gorgeous and the staff is so nice!"

"This is a great hotel. Location is excellent. Interior of the hotel is gorgeous and the staff is so nice!"

United States

Christy

$149 nightly

The price is $165

$165 total

Sep 27 - Sep 28

Total with taxes and fees

The Inn at Patrick Square

A modern lounge area with a brick accent wall, a fireplace, and comfortable seating.

A bar area with a counter, multiple chairs, and a display of bottles and glasses.

A hotel room with a bed, a sofa, a dining table with chairs, a coffee machine, and a TV mounted on the wall.

A multi-story hotel with a prominent entrance, a parking lot, and a landscaped area with a small tree.

8. The Abernathy of Clemson

The Abernathy of Clemson

4.0 star property

Clemson

9.6 out of 10, Exceptional, (648 reviews)

9.6/10

Exceptional

(648 reviews)

"Great location, friendly staff, and large rooms."

"Great location, friendly staff, and large rooms."

United States

Robert

$141 nightly

The price is $157

$157 total

Oct 11 - Oct 12

Total with taxes and fees

The Abernathy of Clemson

A hotel room with two beds, a desk with a lamp, a TV, and a bathroom with a mirror and sink.

A hotel reception area with a reception desk, a television, and a sign indicating 'Quality by Choice Hotels'.

A dining area with tables and chairs, framed artwork on the wall, and a view through large windows.

A Quality Inn by Choice Hotels with a clear sky and autumn foliage in the background.

9. Quality Inn & Suites Easley - Greenville

Quality Inn & Suites Easley - Greenville

2.5 star property

Easley

7.0 out of 10, Good, (514 reviews)

7.0/10

Good

(514 reviews)

"Perfect for just an overnight stay"

"Perfect for just an overnight stay"

United States

Mariah

$64 nightly

The price is $71

$71 total

Sep 29 - Sep 30

Total with taxes and fees

Quality Inn & Suites Easley - Greenville

A spacious living room with a sofa, armchairs, and a coffee table. There are two framed paintings on the wall and a large window providing natural light.

A hotel room with a bed, desk, chair, and a television.

A swimming pool with lounge chairs and a lifeguard chair, surrounded by a fence and a building.

A gym with exercise equipment, a treadmill, and a mirror.

10. Baymont by Wyndham Easley/Greenville

Baymont by Wyndham Easley/Greenville

2.5 star property

Easley

7.4 out of 10, Good, (882 reviews)

7.4/10

Good

(882 reviews)

"The staff was very friendly and helpfull and the breakfast was good"

"The staff was very friendly and helpfull and the breakfast was good"

United States

Dione

$73 nightly

The price is $81

$81 total

Sep 27 - Sep 28

Total with taxes and fees

Baymont by Wyndham Easley/Greenville

A modern waiting area with two chairs, a small table, a potted plant, and a wall-mounted clock.

A hotel room with a bed, a TV, a microwave, and a bathroom with a jacuzzi.

A reception area with a marble-patterned counter, a glass door leading outside, and a tiled floor.

A clear blue swimming pool with lounge chairs and umbrellas, surrounded by a fence and a building with a brick facade.

11. Days Inn by Wyndham Easley/Greenville/Clemson Area

Days Inn by Wyndham Easley/Greenville/Clemson Area

2.0 star property

Easley

6.4 out of 10, (905 reviews)

6.4/10

(905 reviews)

"Everithing nice Just need at little more House skeeping"

"Everithing nice Just need at little more House skeeping"

United States

Orlando

$62 nightly

The price is $69

$69 total

Sep 24 - Sep 25

Total with taxes and fees

Days Inn by Wyndham Easley/Greenville/Clemson Area

A modern office space with a desk, computer, and patterned chairs.

A hotel breakfast area with a self-serve station, including a refrigerator, coffee machine, and fruit display.

A hotel room with a large bed, a desk, a chair, a mirror, and a framed picture on the wall.

A Holiday Inn Express hotel with a stone facade, large windows, and a parking lot.

12. Holiday Inn Express & Suites Clemson by IHG

Holiday Inn Express & Suites Clemson by IHG

2.5 star property

Clemson

8.8 out of 10, Excellent, (991 reviews)

8.8/10

Excellent

(991 reviews)

"Wonderful place to stay."

"Wonderful place to stay."

United States

John

$129 nightly

The price is $143

$143 total

Sep 27 - Sep 28

Total with taxes and fees

Holiday Inn Express & Suites Clemson by IHG

A modern kitchen area with a bar counter and seating.

A modern bar area with high stools and a poolside view.

A modern living room with a grey sofa, purple and orange cushions, a coffee table with magazines, and a large window with patterned curtains.

A vending area with snacks and beverages, including chips and soda.

13. Hampton Inn Clemson-University Area

Hampton Inn Clemson-University Area

2.5 star property

Clemson

8.8 out of 10, Excellent, (650 reviews)

8.8/10

Excellent

(650 reviews)

"Staff was great especially Crystal. Breakfast was fine. A little hidden by trees so watch out or you could miss entrance. Also, driveway just a little steep to get into lot but once there everything was fine. "

"Staff was great especially Crystal. Breakfast was fine. A little hidden by trees so watch out or you could miss entrance. Also, driveway just a little steep to get into lot but once there everything was fine. "

United States

Blaise

$106 nightly

The price is $117

$117 total

Oct 4 - Oct 5

Total with taxes and fees

Hampton Inn Clemson-University Area

A dining area with a table and chairs, large windows with a view of the outside, and a green sofa.

A hotel room with two beds, a desk, a chair, a TV, and a painting on the wall.

A gazebo with a tiled roof and wooden pillars, surrounded by a fence and potted plants.

A reception desk with a vase of flowers, framed pictures, and a printer.

14. Days Inn by Wyndham Clemson

Days Inn by Wyndham Clemson

3.5 star property

Clemson

6.8 out of 10, (232 reviews)

6.8/10

(232 reviews)

"Very overpriced for a basic hotel. Obviously survives on game day and big events in Clemson."

"Very overpriced for a basic hotel. Obviously survives on game day and big events in Clemson."

United States

David

$85 nightly

The price is $94

$94 total

Sep 24 - Sep 25

Total with taxes and fees

Days Inn by Wyndham Clemson

A hotel hallway with carpeted floors, white walls, and doors on both sides.

A hotel room with a bed, desk, chair, TV, and large windows with a view of trees and a parking lot.

A modern hotel room with a flat-screen TV mounted on a wooden console, a microwave, and a coffee maker. There is a round mirror on the wall and a chair with wheels.

A hotel with a modern design, including a covered entrance and handicap-accessible parking.

15. Hampton Inn Easley

Hampton Inn Easley

2.5 star property

Easley

9.2 out of 10, Wonderful, (739 reviews)

9.2/10

Wonderful

(739 reviews)

"Friendly staff, clean room and great breakfast. Will stay there again:)"

"Friendly staff, clean room and great breakfast. Will stay there again:)"

United States

Liesel

$129 nightly

The price is $143

$143 total

Oct 18 - Oct 19

Total with taxes and fees

Hampton Inn Easley

A white, two-story house with a front porch, surrounded by trees and shrubs.

A dining area with round tables, black chairs, and white tablecloths.

A bedroom with two beds, a TV, and a fireplace.

A two-story building with a white exterior, a front door, and a balcony.

16. Liberty Hall Bed and Breakfast

Liberty Hall Bed and Breakfast

4.0 star property

Pendleton

10.0 out of 10, Exceptional, (101 reviews)

10/10

Exceptional

(101 reviews)

"Excellent bed & breakfast! Beautiful and perfectly located. My daughter was visiting Clemson and it was the perfect location. Will definitely return!"

"Excellent bed & breakfast! Beautiful and perfectly located. My daughter was visiting Clemson and it was the perfect location. Will definitely return!"

United States

Christine

$191 nightly

The price is $212

$212 total

Oct 21 - Oct 22

Total with taxes and fees

Liberty Hall Bed and Breakfast

A spacious porch with wooden flooring, a dining area with a table and chairs, and a view of the surrounding landscape.

A modern bedroom with a large bed, a ceiling fan, and a view of the outdoors through a window.

A modern kitchen with white cabinets, a large TV, wooden flooring, and a dining area with a bench and coffee table.

A spacious living room with a dark leather sofa, a wooden coffee table, and a dining area with a table and chairs. Large windows provide natural light and views of the outdoors.

17. Carolina Camp Cedar

Carolina Camp Cedar

3.5 star property

Pickens

10.0 out of 10, Exceptional, (3 reviews)

10/10

Exceptional

(3 reviews)

"The cottage was clean, staff was so friendly, our stay was quiet and peaceful… it was perfect! Definitely planning to stay there again!"

"The cottage was clean, staff was so friendly, our stay was quiet and peaceful… it was perfect! Definitely planning to stay there again!"

United States

Katlynn

$179 nightly

The price is $198

$198 total

Sep 24 - Sep 25

Total with taxes and fees

Carolina Camp Cedar

A hotel lobby with a reception desk, seating area, and a view of the street outside.

A hotel room with a bed, desk, chair, nightstand, lamp, and a view of the outside through curtains.

A compact bathroom with a white sink, a mirror, a black refrigerator, and a towel rack with wooden hangers.

A reception area with a desk, two chairs, a large water dispenser, and a painting on the wall.

18. Econo Lodge Clemson - University Area

Econo Lodge Clemson - University Area

2.0 star property

Clemson

7.2 out of 10, Good, (158 reviews)

7.2/10

Good

(158 reviews)

"Good location . Good price. Nice and quiet. Unusually good tv show choices. (Much better than last 4 or 5 hotels that I stayed at!)"

"Good location . Good price. Nice and quiet. Unusually good tv show choices. (Much better than last 4 or 5 hotels that I stayed at!)"

United States

Ruth

$86 nightly

The price is $95

$95 total

Oct 12 - Oct 13

Total with taxes and fees

Econo Lodge Clemson - University Area

A Days Inn by Wyndham with a parking lot, a gazebo, and a building with orange and grey architecture.

A modern kitchen with a stone backsplash, a flat-screen TV, and a coffee machine.

A reception desk with a vase of flowers, framed pictures, and a printer.

A Days Inn by Wyndham hotel with a modern design, featuring a covered entrance and a parking lot.

19. Days Inn by Wyndham Clemson

Days Inn by Wyndham Clemson

2.0 star property

Clemson

8.8 out of 10, Excellent, (3 reviews)

8.8/10

Excellent

(3 reviews)

Days Inn by Wyndham Clemson

A cozy interior with a sofa, a small round table with a vase, and a staircase leading to an upper level.

A compact kitchen with a microwave, oven, and built-in shelves.

A cozy living area with a sofa, a patterned rug, and a wooden tray with a remote control and decorative items.

An outdoor seating area with wicker chairs and a table, surrounded by a natural forest setting.

20. The Pendle-Tin

Pendleton

9.8 out of 10, Exceptional, (12 reviews)

9.8/10

Exceptional

(12 reviews)

"Property was cute, cozy and perfect for our short 2 night stay! Clean and distance to campus was great! "

"Property was cute, cozy and perfect for our short 2 night stay! Clean and distance to campus was great! "

United States

Cindy L.

$202 nightly

The price is $224

$224 total

Sep 23 - Sep 24

Total with taxes and fees

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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Top Pickens County Hotel Reviews

Mountain Inn & Suites

Mountain Inn & Suites

10/10 Excellent

"Great customer service, amenities, and breakfast."

Robyn 4-night trip

Posted 2 hours ago

Mountain Inn & Suites

Mint House Greenville Downtown by Kasa

Mint House Greenville Downtown by Kasa

10/10 Excellent

"Great amenities and nearby attractions. Parking was confusing at first and somewhat doesn't make any sense."

Desmond 3-night trip

Posted 2 hours ago

Mint House Greenville Downtown by Kasa

Crowne Plaza Hotel Greenville-I-385-Roper Mtn Rd by IHG

Crowne Plaza Hotel Greenville-I-385-Roper Mtn Rd by IHG

10/10 Excellent

"Nice hotel"

Roderick 1-night trip

Posted 3 hours ago

Crowne Plaza Hotel Greenville-I-385-Roper Mtn Rd by IHG

Comfort Inn & Suites Clemson - University Area

Comfort Inn & Suites Clemson - University Area

10/10 Excellent

"Everything was wonderful ! The property and room were exceptionally clean. The staff was very friendly and helpful. Breakfast was great with many choices. I highly recommend staying here if in the Clemson area."

Charles 1-night trip

Posted 5 hours ago

Comfort Inn & Suites Clemson - University Area

Embassy Suites Greenville Golf Resort & Conference Center

Embassy Suites Greenville Golf Resort & Conference Center

10/10 Excellent

"no matter what or where I go from here on out Embassy wil be my first choice, I just hope there is one in that location"

dexter 2-night trip

Posted 6 hours ago

Embassy Suites Greenville Golf Resort & Conference Center

The Lodge at Flat Rock

The Lodge at Flat Rock

10/10 Excellent

"Staff were exceptionally polite and helpful."

Robert 2-night trip

Posted 6 hours ago

The Lodge at Flat Rock

Inn @ Clemson

Inn @ Clemson

10/10 Excellent

"Staff were truly awesome and very clean facili u I 0"

Chris 1-night trip

Posted 8 hours ago

Best Western Plus Greenville I-385 Inn & Suites

Best Western Plus Greenville I-385 Inn & Suites

8/10 Good

"It was a bit smaller, but comfortable clean. The toilet was a little bit too low for my liking so if you’re tall, I don’t recommend but the shower was good and the breakfast was good."

Dionicio 1-night trip

Posted 2 days ago

Best Western Plus Greenville I-385 Inn & Suites

Grand Bohemian Lodge Greenville, Autograph Collection

Grand Bohemian Lodge Greenville, Autograph Collection

8/10 Good

"Room was not ready. Check in said 4:00 but we had to wait a long time and they couldn’t tell us when our room would be ready."

Sandra 1-night trip

Posted 9 days ago

Grand Bohemian Lodge Greenville, Autograph Collection

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